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HomeChemistryWhat's Monopropylene Glycol? | The Chemistry Weblog

What’s Monopropylene Glycol? | The Chemistry Weblog

Monopropylene glycol additionally recognized merely as propylene is a viscous, colourless liquid with a definite candy style (however please don’t drink it). Nearly odourless, it’s each miscible with water and hygroscopic, i.e. it attracts and absorbs moisture. 

The chemical components of monopropylene glycol is C3H8O2, which can be written as:


This components tells us that it has two alcohol teams, which make it a diol. Its systematic IUPAC title is due to this fact propane-1,2-diol. Monopropylene glycol has the next bodily properties:

  • Molecular mass: 76.095 g·mol−1
  • Actual mass: 76.052429 g/mol
  • Flashpoint: 98.9 °C  
  • Boiling level: 188.2 °C  
  • Melting level/freezing level threshold: −59 °C  
  • Vapour stress: 0.13 mm Hg at 25 °C
  • Density: 1.0361 g/cu cm at 20 °C. 

What’s Monopropylene Glycol Used For?

From antifreeze to meals components, monopropylene glycol has a variety of commercial and industrial functions. A number of the commonest makes use of are outlined under.

  1. Polymers
    Roughly 45% of the commercial use of propylene glycol is within the manufacture of assorted polyester merchandise. It’s used as a chemical feedstock within the large-scale manufacturing of unsaturated polyester resins, that are became thermoset plastic. Throughout this course of, unsaturated maleic anhydride is blended with isophthalic acid to kind a copolymer. The partially unsaturated copolymer then undergoes additional crosslinking. In the meantime, the propylene glycol reacts with propylene oxide to provide oligomers and polymers, that are then used to make polyurethanes.
  2. Meals components
    Monopropylene glycol is taken into account protected for consumption as a result of its low toxicity, particularly in small concentrations. Consequently, it’s typically used as an additive in numerous meals and beverage merchandise, together with coffee-based drinks, ice cream, soda, and whipped cream.
  3. Pharmaceutical merchandise
    A number of forms of pharmaceutical and private care merchandise include monopropylene glycol. It’s a standard ingredient in alcohol-based sanitisers, as an illustration, as a result of it helps to stop the pores and skin from drying.
    Grinding coffee beans in a tank in a factory
    Monopropylene glycol is used as an additive in coffee-based drinks

    Monopropylene glycol can also be used as a solvent in some oral, injectable and topical medicines. Able to dissolving medication which can be insoluble in water, it acts as an excellent solvent and provider for medicines reminiscent of benzodiazepine tablets.

  4. Antifreeze
    A person pouring blue antifreeze into a car engine for the window screen.The low freezing level and excessive boiling level of monopropylene glycol make it an excellent antifreeze and coolant, respectively. When blended with water at 50% answer, monopropylene glycol considerably lowers the freezing level of water and prevents ice crystals from forming throughout chilly climate. Consequently, it’s generally used to de-ice aircrafts earlier than take-off.
  5. E-cigarettes
    Monopropylene glycol is likely one of the primary elements within the liquid present in digital cigarettes. Close up of a woman inhaling from an e-cigaretteThe warmth attributable to inhalation vaporises the chemical compounds contained within the liquid, creating the attribute e-cigarette ‘smoke’.

Is Monopropylene Glycol Secure?

Monopropylene glycol is listed underneath CAS No: 57-55-6. It’s not categorized as posing a big hazard to well being and is taken into account protected sufficient for use as an additive in meals and medicines. It’s additionally protected to move and doesn’t ignite simply.  

Nevertheless, like many different substances, the chance of toxicity rises because the focus will increase. Usually, monopropylene glycol turns into poisonous at ranges above 18 mg/dL, though this may range relying on a person’s physique weight, age and well being standing. 

Propylene Glycol vs Monopropylene Glycol

Propylene glycol is synonymous and interchangeable with monopropylene glycol. So is there a distinction? In a nutshell, no. They’re merely various names for a similar chemical compound that accommodates alcohol teams and propyl teams. 

The systematic IUPAC title of this chemical is propane-1,2-diol. Monopropylene glycol/ propylene glycol can be referred to as:

  • α-Propylene glycol
  • 1,2-Propanediol
  • 1,2-Dihydroxypropane
  • Methyl ethyl glycol
  • Methylethylene glycol

The Use of Monopropylene Glycol in Medication

Monopropylene glycol is especially utilized in medication and different pharmaceutical merchandise as a solvent and provider. Its miscibility with water means it may possibly dissolve medicines which can be in any other case insoluble in water. 

One other good thing about monopropylene glycol is that it may possibly stop topical medicines, reminiscent of lotions and ointments, from drying out. Because of its hygroscopic properties, it may possibly additionally assist to maintain the pores and skin moisturised.

Monopropylene Glycol MSDS

The materials security information sheet (MSDS) for monopropylene glycol accommodates helpful details about the toxicity and hazards of this well-liked solvent, together with an outline of the primary help measures in case of an emergency.

It could additionally embrace different vital particulars, such because the focus. The entire materials security information sheets for the chemical compounds we provide can be found to obtain from our web site

Should you’re a enterprise seeking to purchase high-quality monopropylene glycol, go to our on-line store immediately. Out there in quite a lot of batch sizes, from 2.5 litres proper as much as 200 litre drums, you’re positive to search out the correct answer to your wants. And should you want any assist, merely get in contact with our pleasant customer support crew.



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