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HomeChemistryExtremely environment friendly and quick synthesis of di-iodinated succinimide derivatives from 1,6-enyne...

Extremely environment friendly and quick synthesis of di-iodinated succinimide derivatives from 1,6-enyne and I2 below air at room temperature


With out utilizing any components, a inexperienced and environment friendly process for the preparation of useful di-iodinated succinimide derivatives has been achieved by means of the iodine radical-initiated cascade cyclization of 1,6-enynes. This protocol might be performed in MeCN in open air at room temperature with good to wonderful yields. Notably, this methodology is very atom- and time-economical, secure to function, simple to scale up, and has wonderful practical group compatibility. Furthermore, that is the primary instance of di-iodinolysis cyclization utilizing iodine radical cascade response.

Graphical abstract: Highly efficient and fast synthesis of di-iodinated succinimide derivatives from 1,6-enyne and I2 under air at room temperature

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