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HomeHealth EducationCan Your Bones Profit from Omega-3s?

Can Your Bones Profit from Omega-3s?

By Dr. Susan Brown and Cameron Vazquez, MPH

You’ve heard of omega-3s for mind well being and coronary heart well being, however have you ever heard about omega-3s for bone well being? Given the myriad advantages these essential anti-inflammatory vitamins have on our well being, it was solely pure to discover whether or not these advantages prolong to bone. And certainly, they do. Omega-3 fatty acids have been proven to scale back fracture threat and reduce bone loss, making them one other key nutrient to help bone well being.

Omega-3s and Fracture Danger

Quite a few research assert that omega-3s straight affect fracture threat generally and threat of hip fracture particularly.

A 2015 examine (1) discovered that males who had the very best ranges of polyunsaturated fatty acids (PUFAs), omega-3s, and EPA had the bottom threat of basic fracture in comparison with males with the bottom ranges of PUFAs, omega-3s, and EPA. The ladies on this examine skilled a decrease threat of basic fracture once they had larger ranges of PUFAs.

This examine additionally discovered that day by day fish oil consumption, a substance with excessive concentrations of omega-3s, throughout midlife decreased a girl’s fracture threat by 25% and a person’s fracture threat in late life by 36%.

One other examine analyzing postmenopausal ladies discovered an analogous development when hip fracture. In truth, the examine asserts that the quantity of α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and whole omega-3 polyunsaturated acids (PUFAs) in crimson blood cells is a significant predictor of hip fracture. Increased ranges of omega-3 fat had been related to a decrease threat for fracture. (2)

Omega-6/Omega-3 Ratio and Fracture Danger

Many research cite excessive ranges of PUFAs as protecting in opposition to bone. This contains each omega-6 PUFAs and omega-3 PUFAs. Nonetheless, analysis has discovered that there’s significance within the ratio of omega-6 PUFAs to omega-3 PUFAs. For example, a examine analyzing postmenopausal ladies discovered {that a} larger omega-6/omega-3 ratio predicts the next threat for hip fracture. In truth, the members with the very best n-6/n-3 suffered from double the hip fractures. (2)

It is smart {that a} excessive omega-6 to omega-3 ratio would enhance the danger of hip fracture. It’s well-known that having too many omega-6s in comparison with omega-3s contributes to quite a lot of critical inflammatory illnesses reminiscent of coronary heart illness, most cancers, and autoimmune problems. (3)

Omega-3s and Bone Mineral Density

Not solely does information help that omega-3s dramatically cut back fracture threat, but in addition the analysis means that omega-3s straight affect bone mineral density. That is performed by facilitating bone mineralization, lowering irritation, and defending in opposition to extreme bone breakdown. (4)

Bone mineral loss is the results of an imbalance between bone formation by osteoblast cells and bone resorption by osteoclast cells. Omega-3s can enhance bone-building cell exercise and cut back the exercise of bone breakdown cells. One examine even steered that 4.5 to six grams per day of EPA and DHA can have healing results on bone loss. (5)

Not solely have the bone advantages of omega-3s been replicated in populations all around the world, together with in South Korea (6), China (7), Spain (8), and Iceland (1), however they’ve additionally been seen in research carried out by NASA on astronauts who’ve lived past our world. Astronauts lose bone due to the weightlessness they expertise in house journey. On common, astronauts lose 1 to 1.5% of bone monthly whereas dwelling in house. (9)

To fight this bone loss, researchers investigated the results of omega-3s and located that astronauts who consumed extra fish (and subsequently extra omega-3s) suffered much less bone loss following their return from 4- to 6-month house flights. (10)

Omega-3s and Steroid-Induced Osteoporosis

Glucocorticoids reminiscent of prednisone, are the primary explanation for secondary osteoporosis and osteoporosis earlier than the age of fifty. (11)

Decreasing the injury to the bone from steroid drugs is essential and a current Russian examine means that omega-3 fat may also help. Though this was an animal examine, it demonstrated that omega-3 fat can forestall bone loss from steroid use. That is almost certainly as a result of anti-inflammatory actions of omega-3 fat. (12)

We stay up for extra human research, in addition to newer and extra progressive research sooner or later to substantiate these findings.

Higher Your Bones with Omega-3s

Right here on the Middle for Higher Bones, omega-3 fat rank amongst the essential bone-building vitamins, as does the ratio of omega-6s to omega-3s. Now, with breakthrough know-how, it’s attainable with a easy at-home blood spot check to get a complete evaluation to measure each your omega-3 fat and your omega-6 to omega-3 ratio, and to detect when you have poisonous trans fat.Omega 3 Master class

Click on for References


  1. Harris, T. B., et al. 2015. Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture threat in older adults: The Age, Gene/Surroundings Susceptibility Research. American Journal of Scientific Diet 101(5):947-955.
  2. Orchard, T. S., et al. 2013. The affiliation of crimson blood cell n-3 and n-6 fatty acids with bone mineral density and hip fracture threat within the ladies’s well being initiative. Journal of Bone and Mineral Analysis 28(3):505-515.
  3. Simopoulos, A. P. 2006. Evolutionary points of weight-reduction plan, the omega-6/omega-3 ratio and genetic variation: Dietary implications for continual illnesses. Biomedicine & Pharmacotherapy 60(9):502-507.
  4. Sharma, T. and C. C. Mandal. 2020. Omega-3 fatty acids in pathological calcification and bone well being. Journal of Meals Biochemistry 44(8):e13333.
  5. Fazelnia, F. and N. Khodabandehloo. 2019. Preventive and healing impact of omega-3 supplementation on bone mineral density in individuals aged 60 years and older: A scientific assessment. Inner Medication and Medical Investigation Journal 4(1):9-15.
  6. Moon, H.-J., et al. 2012. Constructive correlation between erythrocyte ranges of n-3 polyunsaturated fatty acids and bone mass in postmenopausal Korean ladies with osteoporosis. Annals of Diet and Metabolism 60(2):146-153.
  7. Chen, Y. M., et al. 2010. Increased sea fish consumption is related to higher bone mass and decrease osteoporosis threat in postmenopausal Chinese language ladies. Osteoporosis Worldwide 21:939-946.
  8. Lavado-García, J., et al. 2018. Lengthy-chain omega-3 polyunsaturated fatty acid dietary consumption is positively related to bone mineral density in regular and osteopenic Spanish ladies. PLoS ONE 13(1):e0190539.
  9. Stavnichuk, M., et al. 2020. A scientific assessment and meta-analysis of bone loss in house vacationers. Npj Microgravity 6:article 13.
  10. NASA (Nationwide Aeronautics and House Administration). 2010. NASA research discover omega-3 might assist cut back bone loss. Science Day by day 11 Might 2010.
  11. Briot, Okay. and C. Roux. 2015. Glucocorticoid-induced osteoporosis. RMD Open 1(1):e000014.
  12. Elbahnasawy, A. S., et al. 2019. Protecting impact of dietary oils containing omega-3 fatty acids in opposition to glucocorticoid-induced osteoporosis. Journal of Diet and Well being 52(4):323-331.


Dr. Susan BrownI’m Dr. Susan Brown. I’m a scientific nutritionist, medical anthropologist, author, and motivational speaker. Study my time-tested 6 step pure strategy to bone well being in my on-line workshops. I stay up for serving to you construct sturdy bones for all times!



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